Assay Detail
Functional
CHEMBL5526169
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at rat CTR expressed in Baby hamster kidney cells incubated for 3 hrs by cAMP assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Kidney |
| Cell Type | Baby hamster kidney cell |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
NN1213 - A Potent, Long-Acting, and Selective Analog of Human Amylin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 10 | 7.44 | 8.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2103758 | PRAMLINTIDE | 4.0 | 1 | 8.74 |
| CHEMBL5563010 | — | — | 1 | 7.84 |
| CHEMBL5568431 | — | — | 1 | 7.79 |
| CHEMBL5560328 | — | — | 1 | 7.77 |
| CHEMBL5566453 | — | — | 1 | 7.52 |
| CHEMBL5561117 | — | — | 1 | 7.43 |
| CHEMBL5567377 | — | — | 1 | 6.99 |
| CHEMBL5568143 | — | — | 1 | 6.85 |
| CHEMBL5567446 | — | — | 1 | 6.07 |
| CHEMBL3989767 | CALCITONIN SALMON | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2103758 | PRAMLINTIDE | EC50 | = | 1.822 | nM | 8.74 |
| CHEMBL5563010 | — | EC50 | = | 14.34 | nM | 7.84 |
| CHEMBL5568431 | — | EC50 | = | 16.21 | nM | 7.79 |
| CHEMBL5560328 | — | EC50 | = | 16.81 | nM | 7.77 |
| CHEMBL5566453 | — | EC50 | = | 30.37 | nM | 7.52 |
| CHEMBL5561117 | — | EC50 | = | 37.16 | nM | 7.43 |
| CHEMBL5567377 | — | EC50 | = | 102.5 | nM | 6.99 |
| CHEMBL5568143 | — | EC50 | = | 141.9 | nM | 6.85 |
| CHEMBL5567446 | — | EC50 | = | 860.6 | nM | 6.07 |
| CHEMBL3989767 | CALCITONIN SALMON | EC50 | = | 0.00014 | nM | - |