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Assay Detail

CHEMBL5528099

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against human THP-1 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type THP-1
Confidence 1 — Organism
Curated By Autocuration

Target

THP-1 (CHEMBL614245)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthetic product-based approach toward potential antileishmanial drug development.
Pal R, Teli G, Akhtar MJ, Matada GSP.
Eur J Med Chem (2024) 263 : 115927 -115927
PubMed 37976706 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.30 4.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5563463 1 4.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5563463 IC50 = 50360.0 nM 4.30