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Assay Detail

CHEMBL5533386

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antitumor activity against human Lymphoma cell line assessed as inhibition of cell growth incubated for 72 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Lymphoma cell line
Confidence 1 — Organism
Curated By Autocuration

Publication

MNK, mTOR or eIF4E-selecting the best anti-tumor target for blocking translation initiation.
Li S, Chen JS, Li X, Bai X, Shi D.
Eur J Med Chem (2023) 260 : 115781 -115781
PubMed 37669595 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.80 5.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5542372 1 5.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5542372 IC50 = 1600.0 nM 5.80