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Assay Detail

CHEMBL5533433

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to JNK3 (unknown origin) assessed as dissociation constant by HotSpot assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Mitogen-activated protein kinase 10 (CHEMBL2637)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Targeting protein kinases for the treatment of Alzheimer's disease: Recent progress and future perspectives.
Li Z, Yin B, Zhang S, Lan Z, Zhang L.
Eur J Med Chem (2023) 261 : 115817 -115817
PubMed 37722288 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 7.34 7.34

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5437462 1 7.34
CHEMBL5574538 1 7.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5437462 Kd = 46.0 nM 7.34
CHEMBL5574538 Kd = 46.0 nM 7.34