Assay Detail
Binding
CHEMBL5537415
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PDGFRbeta (unknown origin) by DiscoverX KINOMEscan assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Platelet-derived growth factor receptor beta (CHEMBL1913) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Emerging opportunities to treat idiopathic pulmonary fibrosis: Design, discovery, and optimizations of small-molecule drugs targeting fibrogenic pathways.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.83 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3764045 | TAS-115 | 1.0 | 1 | 8.15 |
| CHEMBL5591364 | — | — | 1 | 7.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3764045 | TAS-115 | IC50 | = | 7.06 | nM | 8.15 |
| CHEMBL5591364 | — | IC50 | = | 31.0 | nM | 7.51 |