Assay Detail
Functional
CHEMBL5540967
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Inhibition of cell growth of human THP-1 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | THP-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design and Synthesis of Dual-Targeting Inhibitors of sEH and HDAC6 for the Treatment of Neuropathic Pain and Lipopolysaccharide-Induced Mortality.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.60 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL408513 | BELINOSTAT | 4.0 | 1 | 6.40 |
| CHEMBL5567303 | — | — | 1 | 5.50 |
| CHEMBL5570460 | — | — | 1 | 4.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL408513 | BELINOSTAT | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL5567303 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL5570460 | — | IC50 | = | 12300.0 | nM | 4.91 |