Assay Detail
Binding
CHEMBL5541928
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Binding affinity to NanoLuc fused-CITK (unknown origin) expressed in HEK293T cells assessed as dissociation constant NanoBRET Target Engagement Intracellular Kinase Assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293T |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery and Characterization of Selective, First-in-Class Inhibitors of Citron Kinase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 8.02 | 8.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5572737 | — | — | 1 | 8.02 |
| CHEMBL5571434 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5572737 | — | Kd | = | 9.5 | nM | 8.02 |
| CHEMBL5571434 | — | Kd | - | — | - |