Assay Detail
Functional
CHEMBL5543260
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Antiinflammatory activity against TPA-induced CD-1 mouse ear edema model assessed as reduction in ear edema
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of anti-inflammatory natural flavonoids: Diverse scaffolds and promising leads for drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.20 | 6.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL6 | INDOMETHACIN | 4.0 | 1 | 6.57 |
| CHEMBL8996 | ERIODICTYOL | — | 1 | 6.14 |
| CHEMBL9352 | NARINGENIN | — | 1 | 5.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL6 | INDOMETHACIN | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL8996 | ERIODICTYOL | IC50 | = | 720.0 | nM | 6.14 |
| CHEMBL9352 | NARINGENIN | IC50 | = | 1310.0 | nM | 5.88 |