Assay Detail
Functional
CHEMBL5585908
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Cytotoxicity against human HL-60 cells assessed as inhibition of cell viability incubated for 48 hrs by WST-8 assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Plakevulin A induces apoptosis and suppresses IL-6-induced STAT3 activation in HL60 cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.41 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL210842 | PLAKEVULIN A | — | 1 | 5.58 |
| CHEMBL5598016 | — | — | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL210842 | PLAKEVULIN A | IC50 | = | 2630.0 | nM | 5.58 |
| CHEMBL5598016 | — | IC50 | = | 5760.0 | nM | 5.24 |