Assay Detail
ADMET
CHEMBL5609487
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CYP2C9 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-based discovery of novel piperidine-biphenyl-DAPY derivatives as non-nucleoside reverse transcriptase inhibitors featuring improved potency, safety, and selectivity: From piperazine-biphenyl-DAPYs to piperidine-biphenyl-DAPYs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.11 | 5.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL782 | TOLBUTAMIDE | 4.0 | 1 | 5.11 |
| CHEMBL5612014 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL782 | TOLBUTAMIDE | IC50 | = | 7690.0 | nM | 5.11 |
| CHEMBL5612014 | — | IC50 | > | 50000.0 | nM | - |