Assay Detail
ADMET
CHEMBL5609901
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Inhibition of CYP2C9 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery and optimization of thiazole-based quorum sensing inhibitors as potent blockers of Pseudomonas aeruginosa pathogenicity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.79 | 4.79 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5614294 | — | — | 1 | 4.79 |
| CHEMBL5090908 | — | — | 1 | - |
| CHEMBL5613568 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5614294 | — | IC50 | = | 16400.0 | nM | 4.79 |
| CHEMBL5090908 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL5613568 | — | IC50 | > | 25000.0 | nM | - |