Assay Detail
Functional
CHEMBL5634233
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Antiprotozoal activity against Trypanosoma cruzi amastigotes measured after 24 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma cruzi |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Exploring N-myristoyltransferase as a promising drug target against parasitic neglected tropical diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.89 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5641858 | — | — | 1 | 7.70 |
| CHEMBL5646727 | — | — | 1 | 7.22 |
| CHEMBL3357685 | ZELENIRSTAT | 2.0 | 1 | 5.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5641858 | — | EC50 | = | 20.0 | nM | 7.70 |
| CHEMBL5646727 | — | EC50 | = | 60.0 | nM | 7.22 |
| CHEMBL3357685 | ZELENIRSTAT | EC50 | = | 1830.0 | nM | 5.74 |