Assay Detail
Functional
CHEMBL5680694
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human T47D cells assessed as inhibition of cell proliferation incubated for 3 days by CellTiter-Glo Luminescent Cell Viability Assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | T47D |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.00 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3128043 | PF-03758309 | 1.0 | 1 | 9.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3128043 | PF-03758309 | IC50 | = | 0.99 | nM | 9.00 |