Assay Detail
Binding
CHEMBL5713045
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Displacement of biotinylated peptide from BRD4 bromodomain 1 (unknown origin) incubated for 30 mins by AlphaScreen assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.41 | 4.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3770112 | — | — | 1 | 4.41 |
| CHEMBL3770847 | — | — | 1 | - |
| CHEMBL3770199 | — | — | 1 | - |
| CHEMBL3739699 | — | — | 1 | - |
| CHEMBL3770277 | — | — | 1 | - |
| CHEMBL3770214 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3770112 | — | IC50 | = | 38900.0 | nM | 4.41 |
| CHEMBL3770847 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL3770199 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL3739699 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL3770277 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL3770214 | — | IC50 | > | 50000.0 | nM | - |