Assay Detail

CHEMBL615197

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Functional

Inhibitory concentration against Jurkat cells

ChEMBL ↗

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Target

Jurkat (CHEMBL397) ↗

Open DB target context

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Primary target Jurkat

CHEMBL397

Anchored from Assay target.

Protein identity Jurkat

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	Jurkat
Confidence	1 — Organism
Curated By	Intermediate

Target

Jurkat (CHEMBL397) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Antimalarial and antitumor evaluation of novel C-10 non-acetal dimers of 10beta-(2-hydroxyethyl)deoxoartemisinin.

Jeyadevan JP, Bray PG, Chadwick J, Chadwick J, Mercer AE, Byrne A, Ward SA, Park BK, Williams DP, Cosstick R, Davies J, Higson AP, Irving E, Posner GH, O'Neill PM.
J Med Chem (2004) 47 : 1290 -1298
PubMed 14971909 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.11	5.11

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL24704	—	—	1	5.11

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL24704	—	IC50	=	7700.0	nM	5.11