Assay Detail
Binding
CHEMBL615392
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Binding affinity towards 5-hydroxytryptamine 1 receptor was determined
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Serotonin 1 (5-HT1) receptor (CHEMBL2095159) ↗| Type | PROTEIN FAMILY |
| Organism | Rattus norvegicus |
Publication
Central serotonin receptors as targets for drug research.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.25 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL277120 | — | — | 1 | 8.30 |
| CHEMBL9434 | PHENYLPIPERAZINE | — | 1 | 6.87 |
| CHEMBL278509 | — | — | 1 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL277120 | — | Ki | = | 5.0 | nM | 8.30 |
| CHEMBL9434 | PHENYLPIPERAZINE | Ki | = | 135.0 | nM | 6.87 |
| CHEMBL278509 | — | Ki | = | 265.0 | nM | 6.58 |