Assay Detail
Binding
CHEMBL615714
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Inhibition constant of high-affinity 5-HT uptake
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Sodium-dependent serotonin transporter (CHEMBL313) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Inhibition and inactivation of presynaptic cholinergic markers using redox-reactive choline analogs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 4.05 | 4.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL57283 | — | — | 1 | 4.05 |
| CHEMBL57055 | CATECHOLINE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL57283 | — | Ki | = | 90000.0 | nM | 4.05 |
| CHEMBL57055 | CATECHOLINE | Ki | = | 390000.0 | nM | - |