Assay Detail
Binding
CHEMBL615870
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards 5-hydroxytryptamine 1 receptor in rat frontal cortex homogenates using [3H]5-HT as a radioligand
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Frontal cortex |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Serotonin 1 (5-HT1) receptor (CHEMBL2095159) ↗| Type | PROTEIN FAMILY |
| Organism | Rattus norvegicus |
Publication
Ergolines as selective 5-HT1 agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.65 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL291218 | — | — | 1 | 6.89 |
| CHEMBL39769 | — | — | 1 | 6.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL291218 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL39769 | — | IC50 | = | 390.0 | nM | 6.41 |