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Assay Detail

CHEMBL617108

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2A receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 2A (CHEMBL322)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Dihydrobenzofuran analogues of hallucinogens. 4. Mescaline derivatives.
Monte AP, Waldman SR, Marona-Lewicka D, Wainscott DB, Nelson DL, Sanders-Bush E, Nichols DE.
J Med Chem (1997) 40 : 2997 -3008
PubMed 9301661 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 3 5.50 5.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL316527 1 5.70
CHEMBL319415 1 5.40
CHEMBL26687 MESCALINE 1.0 1 5.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL316527 EC50 = 2000.0 nM 5.70
CHEMBL319415 EC50 = 4000.0 nM 5.40
CHEMBL26687 MESCALINE EC50 = 4000.0 nM 5.40