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Assay Detail

CHEMBL617269

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory constant on human 5-hydroxytryptamine 2A receptor transfected in to CHO cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type CHO
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 2A (CHEMBL322)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

New serotonin 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptor antagonists: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones.
Brea J, Rodrigo J, Carrieri A, Sanz F, Cadavid MI, Enguix MJ, Villazón M, Mengod G, Caro Y, Masaguer CF, Raviña E, Centeno NB, Carotti A, Loza MI.
J Med Chem (2002) 45 : 54 -71
PubMed 11754579 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.26 8.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL143027 1 8.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL143027 Ki = 5.495 nM 8.26