Assay Detail
Functional
CHEMBL617479
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonistic activity measured for 5-hydroxytryptamine 2A receptor using [3H]-MDL- 100,907 as radioligand in rat cortical homogenates.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.74 | 9.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL149024 | — | — | 1 | 9.64 |
| CHEMBL101008 | — | — | 1 | 7.83 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL149024 | — | Ki | = | 0.23 | nM | 9.64 |
| CHEMBL101008 | — | Ki | = | 14.8 | nM | 7.83 |