Assay Detail
Functional
CHEMBL617630
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonistic activity on 5-hydroxytryptamine 2B receptor of Rat stomach fundus;ND is not determined
9
Total Activities
9
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Stomach |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
New serotonin 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptor antagonists: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| pA2 | 8 | - | - |
| Kd | 1 | 6.48 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL321682 | — | — | 1 | 6.48 |
| CHEMBL111352 | — | — | 1 | - |
| CHEMBL163012 | — | — | 1 | - |
| CHEMBL263790 | — | — | 1 | - |
| CHEMBL161423 | — | — | 1 | - |
| CHEMBL320572 | — | — | 1 | - |
| CHEMBL155006 | — | — | 1 | - |
| CHEMBL163605 | — | — | 1 | - |
| CHEMBL162901 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL321682 | — | Kd | = | 331.13 | nM | 6.48 |
| CHEMBL111352 | — | pA2 | - | — | - | |
| CHEMBL163012 | — | pA2 | - | — | - | |
| CHEMBL263790 | — | pA2 | - | — | - | |
| CHEMBL161423 | — | pA2 | - | — | - | |
| CHEMBL320572 | — | pA2 | - | — | - | |
| CHEMBL155006 | — | pA2 | - | — | - | |
| CHEMBL163605 | — | pA2 | - | — | - | |
| CHEMBL162901 | — | pA2 | - | — | - |