Assay Detail

CHEMBL618894

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Binding affinity towards rat 5-hydroxytryptamine 2A receptor

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

5-hydroxytryptamine receptor 2A (CHEMBL322) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

5-hydroxytryptamine receptor 2A (CHEMBL322) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target 5-hydroxytryptamine receptor 2A

CHEMBL322

Anchored from Assay target.

Protein identity 5-hydroxytryptamine receptor 2A

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Confidence	8 — Homologous single protein target
Curated By	Autocuration

Target

5-hydroxytryptamine receptor 2A (CHEMBL322) ↗

Type	SINGLE PROTEIN
Organism	Rattus norvegicus

Publication

Current and novel approaches to the drug treatment of schizophrenia.

Rowley M, Bristow LJ, Hutson PH.
J Med Chem (2001) 44 : 477 -501
PubMed 11170639 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	8.85	8.85

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL74355	VOLINANSERIN	3.0	1	8.85

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL74355	VOLINANSERIN	Ki	=	1.4	nM	8.85