Assay Detail
Functional
CHEMBL619027
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for agonist activity at the 5-hydroxytryptamine 4 receptor in the rat tunica muscularis mucosae (TMM) assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Tissue | Muscularis mucosa |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Bridgehead-methyl analog of SC-53116 as a 5-HT4 agonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.00 | 7.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL34291 | — | — | 1 | 7.64 |
| CHEMBL318154 | — | — | 1 | 6.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL34291 | — | EC50 | = | 23.0 | nM | 7.64 |
| CHEMBL318154 | — | EC50 | = | 449.0 | nM | 6.35 |