Compound Detail
CHEMBL318154
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Basic Information
| ChEMBL ID | CHEMBL318154 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YXMKSVRISAZMHG-GTNSWQLSSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
337.9
MW (Da)
2.54
ALogP
4
HBA
2
HBD
67.6
PSA (Ų)
0.83
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.35
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 4 CHEMBL4317 | EC50 | 6.35 | 6.35 | 449.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | EC50 | = | 449.0 | nM | 6.35 | Compound was tested for agonist activity at the 5-hydroxytryptamine 4 receptor i... | 15149647 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15149647 | 10.1016/j.bmcl.2004.04.021 | 5-hydroxytryptamine receptor 4 | 1 |
Data from ChEMBL 36 via Core Engine