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Assay Detail

CHEMBL619029

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Efficient 5-hydroxytryptamine 4 agonist in the rat tunica muscularis mucosae
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Tissue Muscularis mucosa
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 4 (CHEMBL4317)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

5-HT4 receptor ligands: applications and new prospects.
Langlois M, Fischmeister R.
J Med Chem (2003) 46 : 319 -344
PubMed 12540230 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 7.51 7.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL34291 1 7.62
CHEMBL324057 1 7.39

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL34291 EC50 = 23.7 nM 7.62
CHEMBL324057 EC50 = 40.3 nM 7.39