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Assay Detail

CHEMBL619080

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Tested for affinity against 5-hydroxytryptamine 4 receptor in the myenteric plexus of the guinea pig ileum.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Tissue Ileum
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

5-hydroxytryptamine receptor 4 (CHEMBL5017)
Type SINGLE PROTEIN
Organism Cavia porcellus

Publication

5-HT4 receptor ligands: applications and new prospects.
Langlois M, Fischmeister R.
J Med Chem (2003) 46 : 319 -344
PubMed 12540230 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.08 7.08

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL60889 MOSAPRIDE 3.0 1 7.08

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL60889 MOSAPRIDE Ki = 84.0 nM 7.08