Assay Detail
Functional
CHEMBL619136
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Compound was evaluated for cytotoxicity against A2780 cis cell lines.
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A2780 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel imidazothioxanthones: Synthesis, DNA binding and cytotoxicity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.79 | 6.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL353282 | — | — | 1 | 6.32 |
| CHEMBL169245 | — | — | 1 | 6.19 |
| CHEMBL171004 | — | — | 1 | 6.12 |
| CHEMBL171056 | — | — | 1 | 5.75 |
| CHEMBL171026 | — | — | 1 | 5.22 |
| CHEMBL172337 | — | — | 1 | 5.12 |
| CHEMBL434104 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL353282 | — | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL169245 | — | IC50 | = | 650.0 | nM | 6.19 |
| CHEMBL171004 | — | IC50 | = | 760.0 | nM | 6.12 |
| CHEMBL171056 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL171026 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL172337 | — | IC50 | = | 7600.0 | nM | 5.12 |
| CHEMBL434104 | — | IC50 | > | 100000.0 | nM | - |