Assay Detail
Functional
CHEMBL619137
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Relative resistance factor in A2780 cisplatin-resistant line
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A2780 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel imidazothioxanthones: Synthesis, DNA binding and cytotoxicity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.88 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL353282 | — | — | 1 | 6.00 |
| CHEMBL169245 | — | — | 1 | 5.92 |
| CHEMBL171026 | — | — | 1 | 5.89 |
| CHEMBL172337 | — | — | 1 | 5.89 |
| CHEMBL171004 | — | — | 1 | 5.85 |
| CHEMBL171056 | — | — | 1 | 5.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL353282 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL169245 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL171026 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL172337 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL171004 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL171056 | — | IC50 | = | 1800.0 | nM | 5.75 |