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Assay Detail

CHEMBL619142

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Functional
cytotoxic activity toward A2780 ovarian human cell line sensitive (S) to cisplatin in experiment 1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A2780
Confidence 1 — Organism
Curated By Intermediate

Target

A2780 (CHEMBL614004)
Type CELL-LINE
Organism Homo sapiens

Publication

Gold(III) complexes as potential antitumor agents: solution chemistry and cytotoxic properties of some selected gold(III) compounds.
Messori L, Abbate F, Marcon G, Orioli P, Fontani M, Mini E, Mazzei T, Carotti S, O'Connell T, Zanello P.
J Med Chem (2000) 43 : 3541 -3548
PubMed 11000008 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.80 6.90

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL89445 TERPYRIDINE 1 6.90
CHEMBL326518 AU(TERPY) 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL89445 TERPYRIDINE IC50 = 125.0 nM 6.90
CHEMBL326518 AU(TERPY) IC50 = 200.0 nM 6.70