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Assay Detail

CHEMBL621545

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity for 5-hydroxytryptamine 2A serotonin receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Expert

Target

5-hydroxytryptamine receptor 2A (CHEMBL322)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Pyrazino[1,2-a]indoles as novel high-affinity and selective imidazoline I(2) receptor ligands.
Chang-Fong J, Tyacke RJ, Lau A, Westaway J, Hudson AL, Glennon RA.
Bioorg Med Chem Lett (2004) 14 : 1003 -1005
PubMed 15013010 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL269073 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL269073 Ki = 9930.0 nM 5.00