Assay Detail
Functional
CHEMBL621971
Review assay metadata, readout intent, target linkage, and publication context from the same page.
cytotoxic activity toward A2780 ovarian human cell line resistant (R) to cisplatin in experiment 2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A2780 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Gold(III) complexes as potential antitumor agents: solution chemistry and cytotoxic properties of some selected gold(III) compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.44 | 6.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL89445 | TERPYRIDINE | — | 1 | 6.44 |
| CHEMBL332792 | AUCYCLAM | — | 1 | - |
| CHEMBL117106 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL89445 | TERPYRIDINE | IC50 | = | 360.0 | nM | 6.44 |
| CHEMBL332792 | AUCYCLAM | IC50 | > | 120000.0 | nM | - |
| CHEMBL117106 | — | IC50 | > | 120000.0 | nM | - |