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Assay Detail

CHEMBL640588

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]ZM-241385 from A2A receptor in rat striatal membrane
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Tissue Striatum
Subcellular Membrane
Confidence 9 — Direct single protein target
Curated By Expert

Target

Adenosine receptor A2a (CHEMBL302)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Substituted 4-phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives as antagonists for the adenosine A(1) receptor.
van Tilburg EW, van der Klein PA, de Groote M, Beukers MW, IJzerman AP.
Bioorg Med Chem Lett (2001) 11 : 2017 -2019
PubMed 11454470 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.72 5.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL60156 1 5.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL60156 Ki = 1900.0 nM 5.72