Assay Detail
Binding
CHEMBL642178
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Binding affinity at rat brain Adenosine A2A receptor in CHO cells
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 7.55 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL132629 | — | — | 1 | 7.55 |
| CHEMBL133809 | — | — | 1 | - |
| CHEMBL302376 | — | — | 1 | - |
| CHEMBL340998 | — | — | 1 | - |
| CHEMBL133591 | — | — | 1 | - |
| CHEMBL439976 | — | — | 1 | - |
| CHEMBL129903 | — | — | 1 | - |
| CHEMBL338352 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL132629 | — | Ki | = | 28.0 | nM | 7.55 |
| CHEMBL133809 | — | Ki | > | 10.0 | nM | - |
| CHEMBL302376 | — | Ki | > | 10.0 | nM | - |
| CHEMBL340998 | — | Ki | > | 10.0 | nM | - |
| CHEMBL133591 | — | Ki | > | 10.0 | nM | - |
| CHEMBL439976 | — | Ki | > | 10.0 | nM | - |
| CHEMBL129903 | — | Ki | > | 10.0 | nM | - |
| CHEMBL338352 | — | Ki | > | 10.0 | nM | - |