Assay Detail
Binding
CHEMBL643019
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pA2 value was measured in Alpha-2 adrenergic receptor against clonidine in rat vas deferens.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
3-Phenyl analogues of 2-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]-methyl]-1,4-benzodioxan (WB 4101) as highly selective alpha 1-adrenoceptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 5.02 | 6.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL101514 | — | — | 1 | 6.50 |
| CHEMBL2111606 | — | — | 1 | 4.85 |
| CHEMBL2111605 | — | — | 1 | 4.49 |
| CHEMBL287935 | — | — | 1 | 4.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL101514 | — | Kd | = | 316.23 | nM | 6.50 |
| CHEMBL2111606 | — | Kd | = | 14125.38 | nM | 4.85 |
| CHEMBL2111605 | — | Kd | = | 32359.37 | nM | 4.49 |
| CHEMBL287935 | — | Kd | = | 60255.96 | nM | 4.22 |