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Assay Detail

CHEMBL643914

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against Alpha-2 adrenergic receptor in rat vas deferens
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Vas deferens
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Adrenergic receptor alpha-2 (CHEMBL2093864)
Type PROTEIN FAMILY
Organism Rattus norvegicus

Publication

Heteroaromatic analogues of the alpha 2-adrenoreceptor partial agonist clonidine.
Chapleo CB, Butler RC, England DC, Myers PL, Roach AG, Smith CF, Stillings MR, Tulloch IF.
J Med Chem (1989) 32 : 1627 -1630
PubMed 2567783 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.11 7.11

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1215 PHENYLEPHRINE 4.0 1 7.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1215 PHENYLEPHRINE IC50 = 78.0 nM 7.11