Assay Detail
Binding
CHEMBL644700
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Compound was tested for its inhibitory potency against angiotensin I converting enzyme.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Molecular and crystal structures of MDL27,467A hydrochloride and quinapril hydrochloride, two ester derivatives of potent angiotensin converting enzyme inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.08 | 8.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1592 | QUINAPRIL | 4.0 | 1 | 8.08 |
| CHEMBL577 | ENALAPRILAT ANHYDROUS | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1592 | QUINAPRIL | IC50 | = | 8.3 | nM | 8.08 |
| CHEMBL577 | ENALAPRILAT ANHYDROUS | IC50 | = | 3.1 | nM | - |