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Assay Detail

CHEMBL645103

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
In Vitro Alpha-1 adrenergic receptor binding affinity on calf frontal cortex membrane preparation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Frontal cortex
Subcellular Membrane
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Alpha-1A adrenergic receptor (CHEMBL4892)
Type SINGLE PROTEIN
Organism Bos taurus

Publication

Synthesis and biological evaluation of new 2-(4,5-dihydro-1H-imidazol-2-yl)-3,4-dihydro-2H-1,4-benzoxazine derivatives.
Touzeau F, Arrault A, Guillaumet G, Scalbert E, Pfeiffer B, Rettori MC, Renard P, Mérour JY.
J Med Chem (2003) 46 : 1962 -1979
PubMed 12723959 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.96 5.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL14028 1 5.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL14028 Ki = 1100.0 nM 5.96