Assay Detail
Binding
CHEMBL645311
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Compound was evaluated for inhibition of hormone stimulated Adenylate cyclase activity in N18TG2 membranes.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
(Aminoalkyl)indole isothiocyanates as potential electrophilic affinity ligands for the brain cannabinoid receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.12 | 6.56 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13078 | — | — | 1 | 6.56 |
| CHEMBL274833 | — | — | 1 | 6.43 |
| CHEMBL61448 | — | — | 1 | 5.96 |
| CHEMBL431950 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13078 | — | EC50 | = | 275.0 | nM | 6.56 |
| CHEMBL274833 | — | EC50 | = | 370.0 | nM | 6.43 |
| CHEMBL61448 | — | EC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL431950 | — | EC50 | = | 3000.0 | nM | 5.52 |