Assay Detail
Binding
CHEMBL646157
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards Alpha-1 adrenergic receptor
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
1,1-diphenyl-3-dialkylamino-1-silacyclopentane derivatives: A new class of potent and selective 5-HT2A antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.04 | 7.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL134423 | — | — | 2 | 7.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL134423 | — | IC50 | = | 86.0 | nM | 7.07 |
| CHEMBL134423 | — | IC50 | = | 100.0 | nM | 7.00 |