Assay Detail
Binding
CHEMBL646351
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Dissociation constant of [3H]ZM-241385 binding to adenosine A2A receptor(AR)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Fluorosulfonyl-substituted xanthines as selective irreversible antagonists for the A(1)-adenosine receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 9.56 | 9.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL327708 | — | — | 1 | 9.64 |
| CHEMBL144360 | — | — | 1 | 9.57 |
| CHEMBL321218 | — | — | 1 | 9.47 |
| CHEMBL148098 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL327708 | — | Kd | = | 0.23 | nM | 9.64 |
| CHEMBL144360 | — | Kd | = | 0.27 | nM | 9.57 |
| CHEMBL321218 | — | Kd | = | 0.34 | nM | 9.47 |
| CHEMBL148098 | — | Kd | = | - | nM | - |