Assay Detail
Binding
CHEMBL646357
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-CGS- 21680 from Adenosine A2A receptor in rat brain membrane
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Ring-Constrained (N)-methanocarba nucleosides as adenosine receptor agonists: independent 5'-uronamide and 2'-deoxy modifications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.36 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL27443 | — | — | 1 | 7.00 |
| CHEMBL26759 | — | — | 1 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL27443 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL26759 | — | Ki | = | 1910.0 | nM | 5.72 |