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Assay Detail

CHEMBL647733

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against rat adenosine A2A receptor in RBL-2H3 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Cell Type RBL-2H3
Confidence 9 — Direct single protein target
Curated By Expert

Target

Adenosine receptor A2a (CHEMBL302)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Synthesis, biological properties, and molecular modeling investigation of the first potent, selective, and water-soluble human A(3) adenosine receptor antagonist.
Maconi A, Pastorin G, Da Ros T, Spalluto G, Gao ZG, Jacobson KA, Baraldi PG, Cacciari B, Varani K, Moro S, Borea PA.
J Med Chem (2002) 45 : 3579 -3582
PubMed 12166930 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.01 7.01

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL118923 1 7.01

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL118923 Ki = 97.6 nM 7.01