Assay Detail
Binding
CHEMBL650927
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested in vitro for its ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Ultra-short-acting beta-adrenergic receptor blocking agents. 2. (Aryloxy)propanolamines containing esters on the aryl function.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.03 | 7.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL284909 | — | — | 1 | 7.90 |
| CHEMBL31450 | — | — | 1 | 6.90 |
| CHEMBL31036 | — | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL284909 | — | Kd | = | 12.59 | nM | 7.90 |
| CHEMBL31450 | — | Kd | = | 125.89 | nM | 6.90 |
| CHEMBL31036 | — | Kd | = | 501.19 | nM | 6.30 |