Beta-1 adrenergic receptor · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-14Protein identity stays anchored to UniProt B0FL73. Use UniProt B0FL73 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt B0FL73 as the stable identity anchor, then attach disease evidence before program review.
Beta-1 adrenergic receptor
Review this target as Beta-1 adrenergic receptor, mapped to UniProt B0FL73. Sequence length is 467 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-1 adrenergic receptor as ChEMBL target CHEMBL5471, mapped to UniProt B0FL73. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Beta-1 adrenergic receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | B0FL73 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-1 adrenergic receptor |
| UniProt Accession | B0FL73 |
| Component Type | Protein |
| Sequence Length | 467 aa |
Beta-1 adrenergic receptor
Review this target as Beta-1 adrenergic receptor, mapped to UniProt B0FL73. Sequence length is 467 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL443435 | 10.4 | EC50 | 0.03981 | Preclinical |
| CHEMBL30622 | 10.0 | Kd | 0.1 | Preclinical |
| CHEMBL304344 | 9.82 | Kd | 0.1514 | Preclinical |
| CHEMBL1256786 | 9.5 | EC50 | 0.3162 | Approved |
| CHEMBL499 | 9.44 | Kd | 0.3631 | Approved |
| CHEMBL483200 | 9.1 | EC50 | 0.7943 | Preclinical |
| CHEMBL11671 | 9.07 | Kd | 0.8511 | Preclinical |
| CHEMBL173424 | 9.07 | Kd | 0.8511 | Preclinical |
| CHEMBL1788320 | 9.07 | Kd | 0.8511 | Preclinical |
| CHEMBL3085291 | 9.05 | Kd | 0.8913 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 88 | 209 | 6.8 |
| tissue-based format | 6 | 49 | 7.8 |
| assay format | 2 | 5 | 5.7 |
| organism-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 47 | 82 | 6.3 |
| tissue-based format | 20 | 15 | 7.5 |
| organism-based format | 5 | 0 | — |