Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL651572

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested for agonist activity against cloned human beta-1 adrenergic receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Beta-1 adrenergic receptor (CHEMBL213)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Potent, selective benzenesulfonamide agonists of the human beta 3 adrenergic receptor.
Weber AE, Mathvink RJ, Perkins L, Hutchins JE, Candelore MR, Tota L, Strader CD, Wyvratt MJ, Fisher MH.
Bioorg Med Chem Lett (1998) 8 : 1101 -1106
PubMed 9871716 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 6.51 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL12769 1 6.52
CHEMBL276257 1 6.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL12769 EC50 = 300.0 nM 6.52
CHEMBL276257 EC50 = 320.0 nM 6.50