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Assay Detail

CHEMBL651601

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The compound was evaluated for the cytotoxicity against BALB/c 3T3 mouse fibroblasts
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Confidence 1 — Organism
Curated By Intermediate

Target

Mus musculus (CHEMBL375)
Type ORGANISM
Organism Mus musculus

Publication

p-(Methylsulfinyl)phenyl nitrogen mustard as a novel bioreductive prodrug selective against hypoxic tumors.
Kwon CH, Blanco DR, Baturay N.
J Med Chem (1992) 35 : 2137 -2139
PubMed 1597864 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.88 5.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL273595 1 5.92
CHEMBL66804 1 4.73
CHEMBL274253 1 4.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL273595 IC50 = 1200.0 nM 5.92
CHEMBL66804 IC50 = 18700.0 nM 4.73
CHEMBL274253 IC50 = 100000.0 nM 4.00