Assay Detail
Functional
CHEMBL652117
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The compound was tested for cytotoxic potency against CH1 human tumor cell lines.
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CH1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Cytotoxicity of bis(phenylamidinium)furan alkyl derivatives in human tumour cell lines: Relation to DNA minor groove binding
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.16 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL11359 | CISPLATIN | 4.0 | 1 | 7.00 |
| CHEMBL23457 | — | — | 1 | 5.68 |
| CHEMBL25999 | — | — | 1 | 5.44 |
| CHEMBL280419 | — | — | 1 | 5.38 |
| CHEMBL24203 | — | — | 1 | 5.05 |
| CHEMBL23320 | — | — | 1 | 4.82 |
| CHEMBL26009 | — | — | 1 | 4.80 |
| CHEMBL284873 | — | — | 1 | 4.75 |
| CHEMBL24808 | — | — | 1 | 4.35 |
| CHEMBL24057 | FURAMIDINE | -1.0 | 1 | 4.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL11359 | CISPLATIN | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL23457 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL25999 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL280419 | — | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL24203 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL23320 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL26009 | — | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL284873 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL24808 | — | IC50 | = | 44500.0 | nM | 4.35 |
| CHEMBL24057 | FURAMIDINE | IC50 | = | 46500.0 | nM | 4.33 |