Assay Detail
Functional
CHEMBL652985
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Antiviral activity was tested using an enzyme-linked immunosorbent assay (ELISA) to detect HSV-1 (herpes simplex virus type 1) using BSC-1 cells
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cercopithecidae |
| Cell Type | BSC-1 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Deoxy sugar analogues of triciribine: correlation of antiviral and antiproliferative activity with intracellular phosphorylation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.69 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1790617 | — | — | 1 | 5.22 |
| CHEMBL462018 | TRICIRIBINE PHOSPHATE | 2.0 | 1 | 4.70 |
| CHEMBL331237 | TRICIRIBINE | — | 1 | 4.64 |
| CHEMBL315509 | — | — | 1 | 4.19 |
| CHEMBL314567 | — | — | 1 | - |
| CHEMBL2367598 | — | — | 1 | - |
| CHEMBL2112098 | — | — | 1 | - |
| CHEMBL609194 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1790617 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL462018 | TRICIRIBINE PHOSPHATE | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL331237 | TRICIRIBINE | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL315509 | — | IC50 | = | 65000.0 | nM | 4.19 |
| CHEMBL314567 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2367598 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2112098 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL609194 | — | IC50 | > | 100000.0 | nM | - |