Assay Detail
Binding
CHEMBL654417
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Inhibitory activity against Equine Butyrylcholinesterase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Specific targeting of acetylcholinesterase and butyrylcholinesterase recognition sites. Rational design of novel, selective, and highly potent cholinesterase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.31 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1206 | ETHOPROPAZINE | 4.0 | 1 | 7.70 |
| CHEMBL208599 | HUPRINE X | — | 1 | 6.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1206 | ETHOPROPAZINE | Ki | = | 20.0 | nM | 7.70 |
| CHEMBL208599 | HUPRINE X | Ki | = | 120.0 | nM | 6.92 |